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¿Question #228176?
PolarDad: What was the worst plague ever?

Derang3d: I don't have the numbers on hand, but the Spanish Flu was (among) the deadliest, among humans. Otherwise, well all the answers point back towards humanity.
Phil%20Fleischmann: The slaying of the first born.
TheGrimReeple: Capitalism.
0Shea0: .
mattomaw: The yolk rot plaque on Egg Planet in the year 24.376.85:16
Woelf: Reaganomics
pricero1: We don't know about bad ones early in history, but the Black Death was pretty dramatic.
Ruesailmana: Definitely humans